21. November 2018
ARI Seminar Room, Wohllebengasse 12-14, Groundfloor
Abstract: Jiri Mekyska - University of Technology, Brno
Parkinson’s disease (PD) is the second most frequent neurodegenerative disease, which is associated with several motor and non-motor features. Up to 90 % of PD patients develop a motor speech disorder called hypokinetic dysarthria (HD). HD manifests in the field of phonation (e.g. increased instability of articulatory organs, microperturbation in pitch and amplitude), articulation (e.g. rigidity of tongue and jaw, slow alternating motion rate), and prosody (e.g. monopitch, monoloudness). Acoustic analysis of these specific speech/voice disorders enables neurologists and clinical speech therapists to effectively monitor progress of PD as well as to diagnose it. In the frame of this talk we will present a concept of acoustic HD analysis. Consequently, we will present some recent findings focused on prediction of motor (freezing of gait) and non-motor (cognitive) deficits based on the acoustic analysis, we will discuss an application of acoustic HD analysis in treatment effect monitoring (based on high-frequency repetitive transcranial magnetic stimulation), and in PD diagnosis. Finally, we will present some future directions in terms of integration into Health 4.0 systems.